Non-pancreatic hyperlipasemia: A puzzling clinical entity

Table 8 Performance characteristics of amylase in identifying acute pancreatitis in various clinical settings

	Cut-off values (U/L)	Sensitivity (%)	Specificity (%)	LR+	LR-	PPV (%)	NPV (%)
AP overall	> 365	54.6	88.0	4.54	0.52	82.6	64.9
AP without complications	> 354	55.6	93.8	8.93	0.47	92.6	60.1
AP with sepsis	> 560	46.4	92.3	6.04	0.58	76.5	76.2
AP with AKI	> 502	46.3	91.8	5.65	0.58	65.5	83.6
AP with AKI or sepsis	> 271	68.5	70.8	2.35	0.45	65.0	73.9
AP with both complications	> 542	45.0	93.5	6.93	0.59	64.3	86.7

AP: Acute pancreatitis; NPHL: Non-pancreatic hyperlipasemia; LR+: Positive likelihood ratio; LR-: Negative likelihood ratio; PPV: Positive predictive value; NPV: Negative predictive value; AKI: Acute kidney injury.