Evaluation of urea breath test as a diagnostic tool for Helicobacter pylori infection in adult dyspeptic patients

Table 2 ¹³C-urea breath test & ¹⁴C-urea breath test performance

Test type	14C-UBT		13C-UBT
	Optimal sensitivity	Optimal specificity	Optimal sensitivity	Optimal specificity
Urea dose	99.21% with 5 µCi	93.43% with 5 µCi	98.85% with 25 mg	99.13% with 25 mg
Time of assessment after urea administration	98.39% (15 min)	98.71% (15 min)	98.87% (20 min)	98.14% (20 min)
Assessment technique	-98.79% (liquid scintillation counting); -95.40% (solid scintillation UBT)	-87.24% (liquid scintillation counting); -97.46% (solid scintillation UBT)	98.99% (ICOS)	98.55% (ICOS)
Overall accuracy, %	96.15	89.84	96.60	96.93
Safety	Not permitted		Used several times on the same patient and safe for children and pregnant females

ICOS: Integrated cavity output spectrometry; UBT: Urea breath test.