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©The Author(s) 2024.
World J Gastroenterol. Apr 28, 2024; 30(16): 2258-2271
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2258
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2258
Figure 8 Molecular modelling of interaction between lipopolysaccharide and chitin-glucan.
A: Trapping of lipopolysaccharide (LPS) (O antigen moiety colored in yellow and lipid A moiety colored in magenta) by chitin-glucan (CG) (chitin moiety colored in orange and glucan moiety colored in green); B: Folding of CG into a hairpin showing the cavity that hosts LPS in its middle (chitin moiety colored in orange and glucan moiety colored in green); C: Interactions of LPS (O antigen moiety colored in magenta and lipid A moiety colored in blue) with CG (chitin moiety colored in orange and glucan moiety colored in green) via a network of 18 hydrogen bonds (yellow dashed line).
- Citation: Valibouze C, Dubuquoy C, Chavatte P, Genin M, Maquet V, Modica S, Desreumaux P, Rousseaux C. Chitin-glucan improves important pathophysiological features of irritable bowel syndrome. World J Gastroenterol 2024; 30(16): 2258-2271
- URL: https://www.wjgnet.com/1007-9327/full/v30/i16/2258.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i16.2258