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©The Author(s) 2024.
World J Gastroenterol. Apr 28, 2024; 30(16): 2184-2190
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2184
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2184
High exam cost |
Better definition of miRNAs as diagnostic markers in IBD (differentiation between UC and CD and diagnosis of disease activity) |
Few validation studies of miRNAs as blood, fecal, and endoscopic biomarkers |
Better definition of the differences between the expression of fecal, blood, and tissue miRNAs |
Lack of evidence validating miRNAs as a tool for evaluating mucosal healing |
Lack of evidence validating miRNAs as a tool for evaluating histological remission |
Lack of evidence validating miRNAs predictors of clinical and endoscopic responses |
Lack of evidence validating miRNAs in treatment monitoring |
Lack of evidence validating miRNAs as predictors of severe disease |
Insufficient data on the role of miRNAs in modulating the inflammatory response |
Insufficient data on the effects of miRNAs on the intestinal barrier, intestinal microbiota, and the response to probiotics |
- Citation: Oliveira ECS, Quaglio AEV, Grillo TG, Di Stasi LC, Sassaki LY. MicroRNAs in inflammatory bowel disease: What do we know and what can we expect? World J Gastroenterol 2024; 30(16): 2184-2190
- URL: https://www.wjgnet.com/1007-9327/full/v30/i16/2184.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i16.2184