Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models

Figure 7 Inflammatory response in hM3/Ptf1α^(cre) transgenic animal models consistent with the caerulein model. hM3/Ptf1α^(cre)model and its pathological images with inflammatory gene validation. A: Schematic representation of the hM3/Ptf1α^(cre) model; B: H&E staining of pancreatic tissue schematic representation of the modeling methods; C-K: Validation of the significant differentially expressed genes in the transgenic animal hM3/Ptf1α^(cre) model after inducing acute pancreatitis, which were found in the NOD-like receptor and TLR signaling pathways. n = 6 per group, ^aP < 0.01, ^bP < 0.001. CON: Control; CNO: Clozapine N-oxide.