Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models

Figure 5 Apoptosis served as a crucial pathway mediating pancreatic necrosis in acute pancreatitis. Significant differentially expressed (SDE) genes in the apoptotic signaling pathway after comparing the caerulein (CAE) group and CAE + lipopolysaccharide (LPS) group to the control (Con) group. A: Heatmap of SDE genes in the CAE group compared to the Con group; B: Heatmap of SDE genes in the CAE + LPS group compared to the Con group; C-K: Quantitative real-time PCR expression values of commonly significantly different genes in both groups, n = 6 per group, ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. CAE: Caerulein; CON: Control; LPS: Lipopolysaccharide.