Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer

doi:10.3748/wjg.v30.i14.2018

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Apr 14, 2024 (publication date) through Dec 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2024; 30(14): 2018-2037
Published online Apr 14, 2024. doi: 10.3748/wjg.v30.i14.2018

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Figure 7 Sodium butyrate damages the mitochondrial morphology of colorectal cancer cells. A: Sodium butyrate (NaB) inhibits adenosine triphosphate synthesis, but treatment with Fusobacterium nucleatum supernatants (FAB) suppresses this effect; B: After treatment with NaB and FAB, morphological changes of mitochondria were observed under transmission electron microscopy. ^aP < 0.05, ^cP < 0.001.

Citation: Wu QL, Fang XT, Wan XX, Ding QY, Zhang YJ, Ji L, Lou YL, Li X. Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer. World J Gastroenterol 2024; 30(14): 2018-2037
URL: https://www.wjgnet.com/1007-9327/full/v30/i14/2018.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i14.2018