Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer

Figure 5 Effects of sodium butyrate and Fusobacteriumnucleatum on the cell cycle of HCT116 and DLD-1 cells. A: Sodium butyrate (NaB) blocks the cell cycle at G2/M phase, while treatment with Fusobacterium nucleatum has no significant effect on the cell cycle; B: Statistical analysis of flow cytometry results. ns: P > 0.05, ^bP < 0.01, ^cP < 0.001. FAB: Fusobacterium nucleatum supernatant.