Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer

Figure 2 Abundance of butyrate-producing bacteria in fecal samples from colorectal cancer patients is lower compared to that of healthy individuals. A: There were significant differences in bacterial composition between colorectal cancer and normal/adjacent tissues; B: Butyricimonas, Roseburia, Faecalibacterium and other butyric acid producing bacteria are enriched in the feces of healthy individuals; C: The abundance of Lac_Lachnospira, Lac_Roseburia, and Rum_Faecalibacterium in fecal samples of healthy people was significantly higher than that of colorectal cancer patients; D: The abundance of Trichospira and Rochella in the fecal samples of healthy people is significantly higher than that of patients with stage I-IV colorectal cancer, and the abundance of Fecal bacilli in the fecal samples of healthy people and patients with stage I colorectal cancer is higher.