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©The Author(s) 2024.
World J Gastroenterol. Apr 14, 2024; 30(14): 2006-2017
Published online Apr 14, 2024. doi: 10.3748/wjg.v30.i14.2006
Published online Apr 14, 2024. doi: 10.3748/wjg.v30.i14.2006
Table 3 Risk factors for delayed regeneration and failure for restoration of the original volume
Delayed regeneration (total n = 153) | Volume restoration failure (total n = 191) | |||||||
Univariate OR (95%CI) | P value | Multivariate OR (95%CI) | P value | Univariate OR (95%CI) | P value | Multivariate OR (95%CI) | P value | |
Age > 75, yes | 0.67 (0.27-1.68) | 0.45 | - | - | 0.94 (0.46-1.94) | 0.88 | - | - |
Gender, male, yes | 1.14 (0.48-2.67) | 0.77 | - | - | 0.76 (0.40-1.45) | 0.41 | - | - |
BMI > 28 kg/m2, yes | 0.22 (0.03-1.74) | 0.15 | - | - | 0.44 (0.14-1.46) | 0.18 | - | - |
Background, HCC | - | Ref. | - | Ref. | ||||
CCC & CHC | 0.49 (0.13-1.82) | 0.29 | - | - | 1.64 (0.73-3.65) | 0.23 | 0.40 (0.15-1.11) | 0.08 |
Colorectal liver metastasis | 1.83 (0.73-4.56) | 0.19 | - | - | 0.88 (0.34-1.90) | 0.81 | 0.71 (0.22-2.26) | 0.56 |
Others | 1.10 (0.27-4.42) | 0.90 | - | - | 2.39 (0.95-6.00) | 0.07 | 0.28 (0.08-0.97) | 0.44 |
HCV positive, yes | 0.61 (0.26-1.47) | 0.27 | - | - | 0.70 (0.37-1.34) | 0.28 | - | - |
Diabetes mellitus, yes | 0.64 (0.30-1.39) | 0.26 | - | - | 0.55 (0.30-1.00) | 0.05 | 0.69 (0.36-1.35) | 0.28 |
Renal complication, yes | 0.89 (0.18-4.48) | 0.88 | - | - | 1.15 (0.37-3.56) | 0.81 | - | - |
Heavy alcoholic, yes | 0.86 (0.39-1.88) | 0.71 | - | - | 0.84 (0.46-1.53) | 0.56 | - | - |
Preoperative platelet count < 100 × 103/uL, yes | 1.60 (0.28-9.11) | 0.60 | - | - | 4.17 (0.82-21.21) | 0.09 | 4.34 (0.81-23.40) | 0.09 |
Preoperative ALBI score (per 1.0 up) | 1.13 (0.46-2.81) | 0.79 | - | - | 2.76 (1.27-5.97) | 0.01 | 2.63 (1.15-6.04) | 0.02 |
ICG 15 min rate (per 1.0 up) | 1.00 (0.97-1.04) | 0.99 | - | - | 1.00 (0.98-1.04) | 0.58 | - | - |
Liver cirrhosis (F4), yes | 1.94 (0.70-5.38) | 0.20 | - | - | 1.22 (0.47-3.15) | 0.69 | - | - |
Preoperative chemotherapy, yes | 2.01 (0.80-5.03) | 0.14 | - | - | 0.80 (0.34-1.87) | 0.60 | - | - |
Re-hepatectomy, yes | 1.67 (0.40-7.03) | 0.49 | - | - | 0.74 (0.21-2.62) | 0.64 | - | - |
Liver resection percentage (per 1.0% up) | 1.03 (1.00-1.05) | 0.04 | 1.03 (1.00-1.05) | 0.04 | 1.03 (1.01-1.05) | 0.008 | 1.02 (1.00-1.05) | 0.04 |
Intraoperative blood loss > 1000 mL, yes | 1.35 (0.58-3.15) | 0.49 | - | - | 1.41 (0.69-2.86) | 0.34 | - | - |
RBC transfusion, yes | 0.55 (0.12-2.58) | 0.58 | - | - | 1.04 (0.35-3.12) | 0.95 | - | - |
Pringle time > 90 min, yes | 1.82 (0.80-4.14) | 0.16 | - | - | 0.91 (0.46-1.81) | 0.78 | - | - |
Posthepatectomy liver failure grade B/C, yes | 0.95 (0.24-3.60) | 0.92 | - | - | 1.83 (0.61-5.50) | 0.28 | - | - |
Postoperative complication CD grade ≥ 3, yes | 0.54 (0.19-1.53) | 0.24 | - | - | 1.97 (0.95-4.07) | 0.07 | 1.80 (0.83-3.91) | 0.14 |
- Citation: Takahashi K, Gosho M, Miyazaki Y, Nakahashi H, Shimomura O, Furuya K, Doi M, Owada Y, Ogawa K, Ohara Y, Akashi Y, Enomoto T, Hashimoto S, Oda T. Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy. World J Gastroenterol 2024; 30(14): 2006-2017
- URL: https://www.wjgnet.com/1007-9327/full/v30/i14/2006.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i14.2006