Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection

doi:10.3748/wjg.v30.i14.1990

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Apr 14, 2024; 30(14): 1990-2005
Published online Apr 14, 2024. doi: 10.3748/wjg.v30.i14.1990

Table 1 Clinical characteristics of gastric mucosal tumors with different degrees of differentiation, n (%)

	LGIN (n = 96)	HGIN (n = 100)	Differentiated-type (n = 89)	Undifferentiated-type (n = 16)	P value
Gender					0.013
Male	61 (63.5)^a	76 (76.0)^a^,^b	73 (82.0)^b	9 (56.3)^a^,^b
Female	35 (36.5)^a	24 (24.0)^a^,^b	16 (18.0)^b	7 (43.8)^a^,^b
Age (yr) (range)	57 (55-59)^a	63 (61-65)^b	63 (61-65)^b	64 (59-68)^a^,^b	< 0.001
Comorbidity
Diabetes	6 (6.3)	15 (15.0)	9 (10.1)	0 (0.0)	0.108
Hypertension	17 (17.7)	31 (31.0)	19 (21.3)	4 (25.0)	0.161
Cardiovascular disease	5 (5.2)	8 (8.0)	9 (10.1)	2 (12.5)	0.572
Liver cirrhosis	5 (5.2)	1 (1.0)	2 (2.2)	0 (0.0)	0.265
Chronic pulmonary disease	2 (2.1)	6 (6.0)	1 (1.1)	0 (0.0)	0.175
Reflux esophagitis	15 (15.6)	12 (12.0)	11 (12.4)	3 (18.8)	0.794
Barrett’s esophagus	4 (4.2)	2 (2.0)	1 (1.1)	0 (0.0)	0.489
Atrophic gastritis	72 (75.0)^a	93 (93.0)^b	84 (94.4)^b	13 (81.3)^a^,^b	< 0.001
Previous gastric cancer	1 (1.0)	0 (0.0)	2 (2.2)	0 (0.0)	0.461
Smoking history	26 (27.1)^a	49 (49.0)^b	45 (50.6)^b	6 (37.5)^a^,^b	0.004
Drinking history	24 (25.0)	31 (31.0)	24 (27.0)	3 (18.8)	0.673
Family history	15 (15.6)	11 (11.0)	19 (21.3)	0 (0.0)	0.074

^aP < 0.05.

^bP < 0.05.

Data in the same row are superscripted with the same letter or have no superscript to indicate a non-significant difference (P > 0.05). Different letters to indicate a significant difference (P < 0.05). LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia.

Citation: Zhu HY, Wu J, Zhang YM, Li FL, Yang J, Qin B, Jiang J, Zhu N, Chen MY, Zou BC. Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection. World J Gastroenterol 2024; 30(14): 1990-2005
URL: https://www.wjgnet.com/1007-9327/full/v30/i14/1990.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i14.1990