Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery

doi:10.3748/wjg.v30.i12.1714

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2024; 30(12): 1714-1726
Published online Mar 28, 2024. doi: 10.3748/wjg.v30.i12.1714

Table 4 Univariate and multivariate analysis of overall survival

Risk factors	Univariate analysis		Multivariate analysis
Risk factors	HR (95%CI)	P value	HR (95%CI)	P value
Age (yr)	1.044 (1.036-1.051)	< 0.01^a	1.038 (1.030-1.046)	< 0.01^a
Sex (female/male)	0.861 (0.730-1.015)	0.074
BMI (kg/m²)	0.959 (0.935-0.984)	0.001^a	0.997 (0.972-1.023)	0.840
T2DM (yes/no)	1.303 (1.038-1.636)	0.022^a	0.941 (0.745-1.189)	0.610
Tumor site (colon/ rectum)	1.422 (1.091-1.853)	0.009^a	0.984 (0.831-1.165)	0.851
Tumor stage (IV/III/II/I)	2.202 (1.979-2.452)	< 0.01^a	2.167 (1.943-2.416)	< 0.01^a
Smoking (yes/no)	1.081 (0.918-1.273)	0.351
Drinking (yes/no)	1.070 (0.901-1.271)	0.438
Hypertension (yes/no)	1.055 (0.879-1.266)	0.564
CHD (yes/no)	1.355 (0.939-1.957)	0.105
Tumor size (≥ 5 cm/< 5 cm)	1.532 (1.305-1.799)	< 0.01^a	1.235 (1.044-1.459)	0.014^a
RDW (lower/higher)	0.664 (0.565-0.780)	< 0.01^a	0.925 (0.774-1.107)	0.396
Hematocrit (lower/higher)	1.693 (1.437-1.995)	< 0.01^a	1.256 (1.041-1.515)	0.017^a
Overall complications (yes/no)	1.903 (1.611-2.248)	< 0.01^a	1.608 (1.357-1.904)	< 0.01^a

^aP value < 0.05.

RDW: Red blood cell distribution width; HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; T2DM: Type 2 diabetes mellitus.

Citation: Peng D, Li ZW, Liu F, Liu XR, Wang CY. Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery. World J Gastroenterol 2024; 30(12): 1714-1726
URL: https://www.wjgnet.com/1007-9327/full/v30/i12/1714.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i12.1714