Effects of Lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis

doi:10.3748/wjg.v30.i11.1556

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Trials Study

World J Gastroenterol. Mar 21, 2024; 30(11): 1556-1571
Published online Mar 21, 2024. doi: 10.3748/wjg.v30.i11.1556

Table 1 Baseline characteristics of the subjects

Characteristic	Treat (n = 86)	Untreat (n = 74)	P value
Age (yr), median (IQR)	58 (51.25, 64.75)	60 (51, 70)	0.219
Sex, n (%)			0.176
Male	68 (79.07)	53 (71.62)
Female	18 (20.93)	21 (28.38)
TBIL (3.0-22.0 μmol/L)	29.26 (21.025, 43.095)	33.875 (26.168, 53.657)	0.117
Alb (35.0-50.0 g/L)	32.75 (25, 39.6)	30.745 (26.575, 34.825)	0.341
Cr (58-110 μmol/L)	64.5 (54.45, 75.325)	60.55 (51.35, 76.925)	0.498
WBC (3.5-9.5 × 10⁹/L)	3.89 (2.728, 5.578)	3.88 (2.9075, 5.06)	0.855
PLT (125.0-350.0 × 10¹²/L)	78 (43.25, 110.25)	69 (48.25, 111.5)	0.943
PT (9.4-12.5 s)	16.15 (14.6, 18.125)	16.25 (14.625, 18.275)	0.986
INR (0.85-1.14)	1.345 (1.216, 1.518)	1.36 (1.193, 1.505)	0.907
CRP (< 10)	4.75 (1.74, 12.8)	4.995 (1.72, 9.403)	0.836

TBIL: Total bilirubin; Alb: Albumin; Cr: Creatinine; WBC: White blood cell; PLT: Platelet; PT: Prothrombin time; INR: International standard ratio; CRP: C-reactive protein.

Citation: Hu YC, Ding XC, Liu HJ, Ma WL, Feng XY, Ma LN. Effects of Lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis. World J Gastroenterol 2024; 30(11): 1556-1571
URL: https://www.wjgnet.com/1007-9327/full/v30/i11/1556.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i11.1556