Treat to target in Crohn’s disease: A practical guide for clinicians

Figure 3 A practical approach to the clinical application of a treat-to-target strategy in clinical practice. ¹Selecting Therapeutic Targets in Inflammatory Bowel Disease II endorsed treatment target: Consider changing therapy if not met. ²Transmural healing is an adjuvant to endoscopic remission. HBI: Harvey Bradshaw Index; PROM: Patient reported outcome measure; PRO2: Patient reported outcome 2; QoL: Quality of life; AP: Abdominal pain; SF: Stool frequency; CRP: C-reactive protein; ULN: Upper limit of normal; FCP: Faecal calprotectin; SES-CD: Simple Endoscopic Score for Crohn’s Disease; CDEIS: Crohn's Disease Endoscopic Index of Severity; IUS: Intestinal ultrasound; MRE: Magnetic resonance enterography.