Effects of endotoxin on expression of ras, p53 and bcl-2 oncoprotein in hepatocarcinogenesis induced by thioacetamide in rats

Table 2 p53 expression and hepatocarcinoma rate in the various study groups

Group	n	FI, x ± s	% cells labeled, x ± s	Cases with positive ras p21 expression	DNA index, x ± s
Sham	5	1	32	1	0
TAA control	6	1.15 ± 0.067	22 ± 12	6	17
TAA + LPS	6	1.32 ± 0.024a	20 ± 8.2	6	33
TAA + ST	6	1.22 ± 0.088a	25 ± 12	6	50
TAA + ST + LPS	6	1.29 ± 0.083a	30 ± 14	6	67
CBRH-7919 cells	1	1.35	9	1

^aP < 0.01 vs TAA control group; ^bP < 0.05 vs TAA + LPS group; ^cP < 0.01 vs TAA + ST group. CBRH-7919: rat hepatocarcinoma cell line.