P21 and CEA expression and AgNOR counts in dimethylhydrazine-induced colon carcinoma in rats

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Sep 15, 1997 (publication date) through Jan 10, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 15, 1997; 3(3): 163-165
Published online Sep 15, 1997. doi: 10.3748/wjg.v3.i3.163

Table 3 The distribution of positive P21 and Carcino Embryonie Antigen (CEA) immunohistochemical staining in rat colonic lesions

Histological types	n	p21 (%)	CEA (%)
Benign
Normal epithelial cell	10	0 (0.0)	0 (0.0)
Adenoma	3	1 (33.3)	0 (0.0)
Dysplasia	10	6 (60.0)	3 (30.0)
Malignant
Well-differentiated adenocarcinoma	20	14 (70.0)	16 (80.0)
Undifferentiated adenocarcinoma	5	1 (20.0)	4 (80.0)
Mucinous adenocarcinoma	9	7 (77.8)	6 (66.7)

P < 0.05 for p21 and CEA between benign and malignant lessions.

Citation: Zhang ZG, Wu JY, Fu XD, Gu DK, Fang F. P21 and CEA expression and AgNOR counts in dimethylhydrazine-induced colon carcinoma in rats. World J Gastroenterol 1997; 3(3): 163-165
URL: https://www.wjgnet.com/1007-9327/full/v3/i3/163.htm
DOI: https://dx.doi.org/10.3748/wjg.v3.i3.163