Effects of γ-interferon on hepatic fibrosis of schistosoma japonicum-infected mice

Table 2 Changes of γ-IFN and extracellular matrix in the liver before and after γ-IFN treatment

Groups(wk)	Cases	γ-IFN				FN				LN				Type I collagen				Type III collagen
		1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+
Non-treated
20	10	5	4	1			3	4	3		2	6	2		6	4			5	2	3
24	10	8	2				5	5			4	2	2		3	5	2		2	5	3
Treated
20	10		5	3	2	7	3				4	6			7	3			5	5
24	10	5	5			3	6	1			4	6		1	7	2		2	6	2

Note: The numbers under 1+, 2+, 3+ or 4+ mean the cases reaching 1+, 2+, 3+ or 4+ grade.