Effects of γ-interferon on hepatic fibrosis of schistosoma japonicum-infected mice

Table 1 Dynamics of γ-IFN and extracellular matrix in the liver of healthy control and infected mice

Groups(wk)	Cases	γ-IFN				FN				LN				Type I coll.				Type III coll.
		1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+	1+	2+	3+	4+
Control
8	10	1				2				2				2				1
16	10	2				2				1				0				2
24	10	1				1				0				1				2
Infected
8	10	9	1			9	1			10				10				9	1
12	10	3	7			8	2			7	3			5	5			5	5
16	10	1	3	3	3		6	4			6	1	3		8	2			6	4
20	10	5	4	1			3	4	3		2	6	2		6	4			5	2	3
24	10	8	2				5	5			4	4	2		3	5	2		2	5	3
28	10	8				8	2			7	3				4	3	3		4	4	2

Note: The numbers under 1+, 2+, 3+ or 4+ mean the cases reaching 1+ , 2+, 3+ or 4+ grade.