Inhibitory effect of sulindac against chemically-induced primary colonic tumors by N-methyl-N-nitrosourea in mice

Table 3 Effect of sulindac on the number of colorectal tumors induced by N-methyl-N-nitrosourea

	Experiment one		Experiment two
	Sulindacgroup	Control group	Control group	Sulindacgroup
No. of mice	24	24	24	24
No. of mice with tumors	19	9	21	20
No. of mice without tumors	5	15	3	4
Incidence of mice with colon tumors (%)1	79.2	37.5	87.5	83.3
No. of tumors2
0	5	15	3	4
1-3	11	8	8	7
4-6	4	1	5	7
7-9	1	0	5	3
10-12	1	0	2	2
13-16	0	0	1	1

¹χ² test, Experiment one: χ² = 7.563, P < 0.01; Experiment two: χ² = 1.003, P > 0.05.

²Wilcoxon rank test, Experiment one: μ = 5.078, P < 0.01; Experiment two: μ = 1.611, P > 0.05.