Adenosine 2A receptor contributes to the facilitation of post-infectious irritable bowel syndrome by γδ T cells via the PKA/CREB/NF-κB signaling pathway

doi:10.3748/wjg.v29.i9.1475

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Mar 7, 2023 (publication date) through Jul 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2023; 29(9): 1475-1491
Published online Mar 7, 2023. doi: 10.3748/wjg.v29.i9.1475

Table 4 The effect of adenosine 2A receptor on the intestinal mobility in post-infectious irritable bowel syndrome mouse

Group	First black stool time (min)	Bristol stool grade
Control (n = 6)	407 ± 10.33	1.00 ± 0.00
PI-IBS (n = 6)	132 ± 12.59^a	2.67 ± 0.52^a
IBS + SCH58261 (n = 6)	246 ± 14.20^c	1.33 ± 0.51^c
IBS + CGS21680 (n = 6)	168 ± 11.38	2.66 ± 0.54

^aP < 0.05 vs the control group.

^cP < 0.05 vs the PI-IBS group.

PI-IBS: Post-infectious irritable bowel syndrome.

Citation: Dong LW, Chen YY, Chen CC, Ma ZC, Fu J, Huang BL, Liu FJ, Liang DC, Sun DM, Lan C. Adenosine 2A receptor contributes to the facilitation of post-infectious irritable bowel syndrome by γδ T cells via the PKA/CREB/NF-κB signaling pathway. World J Gastroenterol 2023; 29(9): 1475-1491
URL: https://www.wjgnet.com/1007-9327/full/v29/i9/1475.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i9.1475