Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure

Figure 6 Effect of stress granules agonist on G3BP1, HIF-1α, lactate dehydrogenase and endoplasmic reticulum stress related molecules in acute liver failure mice liver. A: The expression of G3BP1 and TIA-1 in liver was detected by immunofluorescence; B: The histogram displays the amount of molecules expression; C and D: The detection kits were used to evaluate the content of HIF-1α in liver tissue homogenate, lactate dehydrogenase in serum; E-G: The protein expression levels of G3BP1, TIA-1, ATF4, CHOP, BAX, BCL2, c-cas3 and c-cas9 was detected by western blot. n = 10. Data was shown mean ± SD. ^aP < 0.05 vs normal group; ^bP < 0.05 vs model group.