Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure

Figure 5 Effects of stress granules agonist on histopathology, apoptosis levels, liver function in acute liver failure mice. A: Hepatic histopathological changes were detected by HE staining; B and F: TUNEL stanning was used to detected the level of apoptosis in live liver tissue; C-E: The levels of alanine aminotransferase, aspartate aminotransferase and total bilirubin in the serum of mice were detected by automatic biochemical analyzer; G: The 6 h, 12 h, 18 h, 24 h survival rates of mice in each group were observed. n = 10. Data was shown mean ± SD. ^aP < 0.05 vs normal group; ^bP < 0.05 vs model group. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBIL: Total bilirubin.