Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure

Figure 4 Effect of stress granules on G3BP1 and endoplasmic reticulum stress related molecules in hepatocyte hypoxia model through endoplasmic reticulum stress. A: The expression of G3BP1 in cells was detected by immunofluorescence; B: The expression of TIA-1 in cells was detected by immunofluorescence; C: The histogram displays the amount of molecules expression; D-F: The protein expression levels of G3BP1, TIA-1, ATF4, CHOP, BAX, BCL2, c-cas3 and c-cas9 was detected by western blot. n = 3. ^aP < 0.05 vs normal group; ^bP < 0.05 vs hypoxia group; ^cP < 0.05 vs hypoxia + siRNA-ATF4.