Hamartomatous polyps: Diagnosis, surveillance, and management

Table 2 Malignancy screening for Peutz-Jeghers syndrome[4,8,10,16-18,85,86]

Malignancy	Screening
Breast	Annual self-breast exam beginning at the age of 18. Annual breast exam with MRI or mammography beginning at the age of 25, and as needed
Cervical	Cervical smear annual beginning at the age of 20, and as needed
Colon	Colonoscopy every 1-3 yr beginning at the age of 8, and as needed. Routine surveillance at 18 if baseline endoscopy at age 8 is negative
Pancreas	Annual endoscopic ultrasound or MRCP/ERCP beginning at the age of 30, and as needed
Stomach	EGD every 1-3 yr beginning at the age of 8, and as needed. Routine surveillance at 18 if baseline endoscopy at age 8 is negative
Small bowel	Capsule endoscopy or CT/MRI enterography every 2-3 yr, beginning at the age of 8, and as needed
Testicular	Annual testicular exam and ultrasound beginning at birth
Uterus	Annual pelvic ultrasound and exam beginning at the age of 25, and as needed; consider total hysterectomy once complete with child-bearing

MRI: Magnetic resonance imaging; CT: Computed tomography; MRCP: Magnetic resonance pancreatography; ERCP: Endoscopic retrograde cholangiopancreatography; EGD: Esophagogastroduodenoscopy.