Predictors of early and late hepatocellular carcinoma recurrence

doi:10.3748/wjg.v29.i8.1243

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Feb 28, 2023 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2023; 29(8): 1243-1260
Published online Feb 28, 2023. doi: 10.3748/wjg.v29.i8.1243

Table 2 Predictors of late hepatocellular carcinoma recurrence after curative treatment

Predictors related to HCC characteristics	Ref.	Predictors related to patient characteristics	Ref.	Predictors related to treatment	Ref.
Size > 5 cm	[92]	Liver cirrhosis	[32,41,43,84,93-96]	RFA (vs LR)	[41,88,117-119]
Multifocality	[92,93]	Old age	[41,92]
Microvascular invasion	[92]	Male sex	[93]
AFP > 400 μg/L	[94]	LSM	[43,102]
		Portal hypertension
		SSM (> 70 kPa)	[43]
		Splenic volume (> 165 mL)	[40]
		Platelet count	[43,103,104]
		Esophageal varices	[43,103]
		HBV infection
		High viral load	[105,108]
		Low viral load	[111]
		High HBsAg levels	[84,86,103,107]

AFP: Alpha-fetoprotein; HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; LR: Liver resection; LSM: Liver stiffness; RFA: Radio-frequency ablation; SSM: Splenic stiffness.

Citation: Nevola R, Ruocco R, Criscuolo L, Villani A, Alfano M, Beccia D, Imbriani S, Claar E, Cozzolino D, Sasso FC, Marrone A, Adinolfi LE, Rinaldi L. Predictors of early and late hepatocellular carcinoma recurrence. World J Gastroenterol 2023; 29(8): 1243-1260
URL: https://www.wjgnet.com/1007-9327/full/v29/i8/1243.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i8.1243