Comparison of genomic and transcriptional microbiome analysis in gastric cancer patients and healthy individuals

Figure 3 Shift and diversity of stomach microbiota of healthy controls, gastric cancer patient’s tumor and tumor adjacent tissues depending on microbial source (DNA and RNA). A: Relative mean abundance of the top 5 microbiota at the phylum; B: Top 7 microbiota at the family; C: Top 7 microbiota at the genus level. Formal comparisons between groups were evaluated by analysis of similarity (PERMANOVA); D: Venn diagrams show the number of common and group-specific phylotypes comparing each study group at the DNA and RNA levels; E: Principal coordinate analysis of bacterial beta diversity of all study groups at the phylum level; F and G: Comparison of bacterial alpha diversity: Bacterial richness and bacterial diversity. ^aq < 0.05, ^bq < 0.01, ^dq < 0.0001.