Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway

doi:10.3748/wjg.v29.i44.5919

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Nov 28, 2023 (publication date) through Jul 31, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2023; 29(44): 5919-5934
Published online Nov 28, 2023. doi: 10.3748/wjg.v29.i44.5919

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Figure 4 Tousled-like kinase 1 inhibition diminished proliferation and augmented apoptosis in gastric cancer cell lines. A and B: 5-ethynyl-2`-deoxyuridine (EdU) assay showing the effects of Tousled-like kinase 1 (TLK1) suppression on AGS cell proliferation; C and D: EdU assay revealing the impact of TLK1 knockdown on HGC27 cell proliferation; E and F: Flow cytometry evaluating the effects of TLK1 inhibition on apoptosis in AGS and HGC27 cell lines. ^aP < 0.05. EdU: 5-ethynyl-2`-deoxyuridine; shNC: Short hairpin RNA of negative control.

Citation: Sun RC, Li J, Li YX, Wang HZ, Dal E, Wang ML, Li YX. Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway. World J Gastroenterol 2023; 29(44): 5919-5934
URL: https://www.wjgnet.com/1007-9327/full/v29/i44/5919.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i44.5919