Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway

Figure 3 Tousled-like kinase 1 knockdown attenuated clonal formation, invasion, and migration in gastric cancer cell lines. A: Western blot revealing the impact of Tousled-like kinase 1 (TLK1) knockdown on AGS and HGC27 cell lines; B and C: Effects of TLK1 suppression on clonogenesis in AGS and HGC27 cell lines; D and E: Transwell assay disclosing the effects of TLK1 knockdown on AGS cell invasion and migration; F and G: Transwell assay demonstrating the influences of TLK1 suppression on HGC27 cell invasion and migration. ^aP < 0.05. TLK1: Tousled-like kinase 1; shNC: Short hairpin RNA of negative control.