Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway

doi:10.3748/wjg.v29.i44.5919

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Nov 28, 2023 (publication date) through Jul 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2023; 29(44): 5919-5934
Published online Nov 28, 2023. doi: 10.3748/wjg.v29.i44.5919

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Figure 2 Tousled-like kinase 1 upregulation potentiated tumorigenesis in gastric cancer cell lines. A: Western blot demonstrated the effects of Tousled-like kinase 1 (TLK1) overexpression in SGC7901 cells; B and C: Impact of TLK1 overexpression on clonogenesis in SGC7901 cells; D and E: 5-ethynyl-2`-deoxyuridine assay evaluating the influence of TLK1 overexpression on SGC7901 cell proliferation; F and G: Transwell assay showing the effects of TLK1 overexpression on SGC7901 cell invasion and migration. ^aP < 0.05. TLK1: Tousled-like kinase 1; NC: Negative control; OE: Overexpression; EdU: 5-ethynyl-2`-deoxyuridine.

Citation: Sun RC, Li J, Li YX, Wang HZ, Dal E, Wang ML, Li YX. Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway. World J Gastroenterol 2023; 29(44): 5919-5934
URL: https://www.wjgnet.com/1007-9327/full/v29/i44/5919.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i44.5919