Changing trends and characteristics of peptic ulcer disease: A multicenter study from 2010 to 2019 in Korea

doi:10.3748/wjg.v29.i44.5882

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Nov 28, 2023 (publication date) through Jan 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2023; 29(44): 5882-5893
Published online Nov 28, 2023. doi: 10.3748/wjg.v29.i44.5882

Table 1 Baseline characteristics of all patients with peptic ulcer disease, n (%)

	Total (n = 26785)
Age ≥ 65 yr	10392 (38.8)
Men	15544 (58.0)
RUT or serology	19601 (73.2)
Gastric ulcer	18527 (69.2)
Duodenal ulcer	8377 (31.3)
Diagnosis
Hypertensive disorder	4773 (17.8)
Diabetes mellitus	2239 (8.4)
Hyperlipidemia	2038 (7.6)
Chronic kidney disease	1282 (4.8)
Ischemic heart disease	2221 (8.3)
Cerebrovascular disease	812 (3.0)
Chronic liver disease	1436 (5.4)
Osteoarthritis	425 (1.6)
Chronic obstructive lung disease	515 (1.9)
Medication
Aspirin	4068 (15.2)
Other antiplatelet agent¹	3065 (11.4)
Clopidogrel	2386 (8.9)
Cilostazole	691 (2.6)
NSAID	5342 (19.9)
Warfarin	579 (2.2)
DOAC	297 (1.1)
Steroid	3404 (12.7)
Antidepressant	6308 (23.6)
Bisphosphonate	488 (1.8)
Immunosuppressant	578 (2.2)

¹Antiplatelet agents other than aspirin include clopidogrel, cilostazole, ticlopidine, triflusal, ticagrelor, and prasugrel.

RUT: Rapid urease test; NSAIDs: Nonsteroidal anti-inflammatory drugs; DOAC: Direct oral anticoagulant.

Citation: Choi YJ, Kim TJ, Bang CS, Lee YK, Lee MW, Nam SY, Shin WG, Seo SI. Changing trends and characteristics of peptic ulcer disease: A multicenter study from 2010 to 2019 in Korea. World J Gastroenterol 2023; 29(44): 5882-5893
URL: https://www.wjgnet.com/1007-9327/full/v29/i44/5882.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i44.5882