Helicobacter pylori infection in Xinjiang Uyghur Autonomous Region: Prevalence and analysis of related factors

Figure 4 Helicobacter pylori infection associated with elevated grade of chronic/active gastritis and intestinal metaplasia. A: Patient with severe chronic gastritis (grade 3) in the gastric wall biopsy tissue; inflammatory cell infiltration can be seen throughout the lamina propria of the mucosa [hematoxylin and eosin (H&E, 40 ×)]; B: Infiltrating inflammatory cells were mainly lymphocytes, with scattered neutrophils, indicating chronic gastritis combined with active gastritis (H&E, 200 ×); C: Gastric glands were infected by Helicobacter pylori (H. pylori) and were accompanied by severe intestinal metaplasia (H&E, 400 ×); D: H. pylori infection was confirmed by immunohistochemistry (DAB, 400 ×); all images were from the same patient, orange arrows in C and D indicates distribution of H. pylori.