Helicobacter pylori infection in Xinjiang Uyghur Autonomous Region: Prevalence and analysis of related factors

Table 2 Comparison of differences between immunohistochemical staining and ¹⁴C urea breath test for detecting Helicobacter pylori infection (n = 3944)

			H. pylori positive rate (%)
			Positive1	Negative1	P value1	Positive2	Negative2	P value (single vs multiple biopsy)2
14C UBT (total, n = 3944)		Positive	1176 (29.8%)	685 (17.4%)	P < 0.001	1962 (49.7%)	1982 (50.3%)	-
		Negative	101 (2.6%)	1982 (50.3%)
Subgroup	Single biopsy (1 piece, n = 3476)	Positive	987 (28.4%)	608 (17.5%)	P < 0.001	1068 (30.7%)	2408 (69.3%)	P < 0.001
		Negative	81 (2.3%)	1800 (51.8%)
	Multiple biopsies (≥ 2 pieces, n = 468)	Positive	189 (40.4%)	77 (16.5%)	P < 0.001	209 (44.7%)	259 (55.3%)
		Negative	20 (4.3%)	182 (38.9%)

¹Immunohistochemical staining.

²Immunohistochemical staining & ¹⁴C urea breath test combined.

¹⁴C UBT: ¹⁴C urea breath test; H. pylori: Helicobacter pylori.