Expression characteristics of peripheral lymphocyte programmed death 1 and FoxP3+ Tregs in gastric cancer during surgery and chemotherapy

Figure 1 Programmed death 1 expression on all T cell subsets of healthy donors and preoperative patients with gastric cancer. A: The scatter and histogram plots of one representative patient are illustrated. The relationships between the diagrams are indicated by arrows and gates (R1, R2, and R3); B-G: The percentages of total programmed death 1⁺ (PD-1⁺) cells (B), CD4⁺PD-1⁺ (C), CD8⁺PD-1⁺ (D), CD45RO⁺PD-1⁺ (E), CD4⁺CD45RO⁺PD-1⁺ (F), and CD8⁺CD45RO⁺PD-1⁺ (G) cells out of the total peripheral lymphocytes from patients and healthy donors are shown. The P value was calculated using a Student’s t-test or Wilcoxon rank sum test.