Diagnostic and economic value of carcinoembryonic antigen, carbohydrate antigen 19-9, and carbohydrate antigen 72-4 in gastrointestinal cancers

Table 9 Subgroup analysis of area under the curve for gastric cancer, colorectal cancer and gastrointestinal cancers

	Gastric cancer			Colorectal cancer			Gastrointestinal cancer
	CEA	CA19-9	CA72-4	CEA	CA19-9	CA72-4	CEA	CA19-9	CA72-4
Whole	0.625	0.577	0.570	0.736	0.649	0.598	0.705	0.627	0.590
≥ 60 years	0.585	0.521	0.544	0.701	0.614	0.577	0.675	0.592	0.572
< 60 years	0.578	0.571	0.570	0.683	0.616	0.593	0.648	0.598	0.583
HC	0.570	0.570	0.525	0.584	0.539	0.514	0.584	0.554	0.526
AC	0.595	0.544	0.547	0.724	0.637	0.577	0.696	0.615	0.571
CIS	0.551	0.478	0.542	0.540	0.536	0.526	-	-	-
Stage I	0.554	0.525	0.565	0.675	0.546	0.512	-	-	-
Stage II	0.603	0.489	0.591	0.781	0.657	0.578	-	-	-
Stage III	0.658	0.645	0.603	0.770	0.642	0.565	-	-	-
Stage IV	0.739	0.614	0.634	0.810	0.778	0.698	-	-	-

The bold font indicates that the area under the curve value was more than 0.7. CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; CA72-4: Carbohydrate antigen 72-4; HC: Health checkup; AC: Active consultation; CIS: Carcinoma in situ.