Enhanced glucose homeostasis via Clostridium symbiosum-mediated glucagon-like peptide 1 inhibition of hepatic gluconeogenesis in mid-intestinal bypass surgery

doi:10.3748/wjg.v29.i39.5471

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Oct 21, 2023 (publication date) through Jun 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2023; 29(39): 5471-5482
Published online Oct 21, 2023. doi: 10.3748/wjg.v29.i39.5471

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Figure 6 Diagram of the mechanism of improved glucose metabolism after mid-small intestine bypass. GLP-1: Glucagon-like peptide 1; TGR5: Takeda G protein-coupled receptor 5; FXR: Farnesoid X receptor; LCA: Lithocholic acid; PCK1: Phosphoenolpyruvate carboxykinase 1; G6PC: Glucose-6-phosphatase.

Citation: Luo X, Tao F, Tan C, Xu CY, Zheng ZH, Pang Q, He XA, Cao JQ, Duan JY. Enhanced glucose homeostasis via Clostridium symbiosum-mediated glucagon-like peptide 1 inhibition of hepatic gluconeogenesis in mid-intestinal bypass surgery. World J Gastroenterol 2023; 29(39): 5471-5482
URL: https://www.wjgnet.com/1007-9327/full/v29/i39/5471.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i39.5471