Leukocyte immunoglobulin-like receptor B2 overexpression as a promising therapeutic target and noninvasive screening biomarker for colorectal cancer

Figure 4 Screening and diagnostic efficacy of serum leukocyte immunoglobulin-like receptor B2 concentration. A: Comparison of serum leukocyte immunoglobulin-like receptor B2 (LILRB2) concentrations among colorectal cancer (CRC) patients, adenoma patients and healthy controls; B: Comparison of serum LILRB2 concentrations before and after radical surgery; C and D: Comparison of serum LILRB2 concentrations between samples with different infiltration depths; E: Comparison of serum LILRB2 concentrations between samples with different degrees of differentiation; F: Sensitivity, specificity and accuracy of serum LILRB2, carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) for the diagnosis of CRC; G: The receiver operating characteristic curve and area under the curve of serum LILRB2, CEA and CA19-9 concentrations in the diagnosis of CRC. LILRB2: Leukocyte immunoglobulin-like receptor B2; CRC: Colorectal cancer; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; ROC: Receiver operating characteristic curve; AUC: Area under the curve. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001.