Lowering the threshold of alanine aminotransferase for enhanced identification of significant hepatic injury in chronic hepatitis B patients

Figure 2 Multiple logistic regression analysis. A: Multiple logistic regression analysis of clinical parameters of chronic hepatitis B patients in HBeAg-positive grey zones associated with significant hepatic injury; B: Multiple logistic regression analysis of clinical parameters of chronic hepatitis B patients in HBeAg-negative grey zones associated with significant hepatic injury; C: Receiver operating characteristic (ROC) curves of aspartate aminotransferase-to-platelet ratio index (APRI), fibrosis score based on four factors (FIB-4), and gamma-glutamyl transpeptidase-to-platelet ratio (GPR) in the prediction of significant hepatic injury (SHI) in HBeAg-positive grey zones; D: ROC curves of APRI, FIB-4, and GPR in the prediction of SHI in HBeAg-negative grey zones. PLT: Platelet; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; ALB: Albumin; APRI: Aspartate aminotransferase-to-platelet ratio index; FIB-4: Fibrosis score based on four factors; GPR: Gamma-glutamyl transpeptidase-to-platelet ratio.