Simultaneous rectal neuroendocrine tumors and pituitary adenoma: A case report and review of literature

Figure 4 Tumor metastasis was observed in the peri-intestinal lymph nodes (4/15). A and B: Laparoscopic low anterior resection with total mesorectal excision was performed 5 mo after diagnosis of the rectal lesions. Central lymph nodes were selected from the lesion for hematoxylin–eosin staining to evaluate the metastasis of neuroendocrine cells (A: 100 ×, B: 400 ×); C-E: Immunohistochemical detection to evaluate the expression and distribution of neuroendocrine markers SSTR2, syn, and CgA in central lymph nodes (400 ×); F: Ki-67 expression in central lymph nodes by immunohistochemistry (400 ×).