Very early onset perinatal constipation: Can it be cow’s milk protein allergy?

Table 2 Relative frequencies of Hirschsprung’s disease vs cow’s milk protein allergy in infants with very early-onset constipation

Ref.	HD (%)	CMPA (%)
Burge and Drewett[18]	38.1
Kubota et al[19]	34.6	65.4
Van Leeuwen et al[20]	25.0
Keckler et al[11]	13.0
Cheng et al (unpublished observation)	8.0	92.0

CMPA: Cow’s milk protein allergy; HD: Hirschsprung’s disease.