Hepatitis B virus infection in patients with Wilson disease: A large retrospective study

Table 3 Characteristics of patients with Wilson disease and chronic hepatitis B: Diagnostic parameters of Wilson disease

Case	Neurologic signs	KF rings	Cerulo plasmin (mg/L)	Urinary copper/after PC (μg/24 h)	Hepatic copper (μg/g/dw)	Mutation analysis	WD score
1	No	P	65.0	177/1600	ND	ND	5
2	No	P	50.0	1222/4250	ND	ND	6
3	No	P	95.0	1818/2266	ND	ND	6
4	Yes	P	187.0	434/ND	ND	ND	7
5	No	P	172.0	107/1295	347	ND	6
6	No	P	216.0	431/1436	1165	ND	6
7	No	P	50.0	5171/15398	ND	ND	6
8	No	P	250.0	305/1933	1173	ND	6
9	No	N	74.0	474/1500	926	3532G>T/3532G>T	10
10	No	P	84.0	595/1725	ND	2755C>G/2975C>T	10
11	No	N	135.0	1297/2984	ND	588C>A/2333G>T	7
12	No	P	78.4	160/1773	741	2975C>T/2975C>T	11
13	No	P	129	855/2505	ND	ND	5
14	No	P	31.0	310/1984	1067	3809 >G/	9
15	No	N	104.0	187/1836	896	0	4
16	Yes	P	86.5	237/2374	404	ND	10
17	No	P	83.1	64/714	265	2975C>T/	7
18	No	P	43.0	155/171	906	2804C>T/2810delT	11
19	No	P	63.0	584/2473	ND	2666G>T/2333G>T	10

WD: Wilson disease; KF rings: Kayser-Fleischer rings; ND: Not done; PC: Penicillamine challenge; N: Negative; P: Positive.