Validation of the albumin-bilirubin score for identifying decompensation risk in patients with compensated cirrhosis

Table 2 Predictors of decompensation in patients with compensated cirrhosis

Variable	Univariate		Multivariate
	Hazard ratio (95%CI)	P value	Adjusted hazard ratio (95%CI)	P value
Age	1.01 (0.97-1.05)	0.47	1.01 (0.97-1.06)	0.56
Male	0.58 (0.22-1.50)	0.26	0.55 (0.18-1.69)	0.29
Creatinine	1.20 (0.83-1.74)	0.31
Albumin	0.10 (0.03-0.26)	< 0.001
Bilirubin	1.21 (1.02-1.43)	0.02
AST	1.00 (0.99-1.00)	0.34
ALT	1.01 (1.00-1.02)	0.01
Platelets	0.99 (0.98-1.00)	0.27
INR	1.58 (0.11-22.29)	0.73
ALBI score	8.31 (3.48-19.85)	< 0.001	4.18 (1.40-12.53)	0.01
MELD score	1.11 (1.02-1.21)	0.01	1.07 (0.92-1.24)	0.34
ALBI-FIB4 score	2.30 (1.60-3.31)	< 0.001	1.73 (0.82-3.64)	0.15
FIB-4 score	1.02 (0.92-1.13)	0.67
Child-Pugh score	1.98 (1.15-3.39)	0.01	1.26 (0.61-2.58)	0.54

AST: Aspartate transaminase; ALT: Alanine transaminase; INR: International normalized ratio; MELD: Model for end-stage liver disease; ALBI: Albumin-bilirubin; FIB-4: Fibrosis-4; CI: Confidence interval.