Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells

Figure 4 Poly(A)-specific ribonuclease promotes tumor growth in vivo. A: Representative image of tumors separated from nude mice; B and C: Tumor volume and weight were measured in nude mice; D and E: Representative bioluminescence imaging (BLI) images and quantification of BLI in the tumor regions of nude mice; F: Representative images of Ki-67 staining in tumors isolated from the nude mice. Scale bars are indicated in the upper left corner of the picture (Bar = 50 μm). Assays were conducted in triplicate. ^cP < 0.001, mean ± SD is shown. sh PARN: Poly(A)-specific ribonuclease shRNA; sh-NC: Control shRNA.