Poly(A)-specific ribonuclease protein promotes the proliferation, invasion and migration of esophageal cancer cells

Figure 1 Exploration of the downstream molecular mechanism of poly(A)-specific ribonuclease in esophageal cancer cells. A: Human apoptosis antibody array analysis was performed in Eca-109 cells transfected with control shRNA or poly(A)-specific ribonuclease shRNA; B: Differences in the human apoptotic antibody array were visualized; C: Densitometry analysis was performed, and the gray values of differentially expressed proteins are shown; D: The expression of the target protein pathway in Eca-109 cells was observed by western blot. The data are expressed as the mean ± SD, ^aP < 0.05, ^bP < 0.01. sh PARN: Poly(A)-specific ribonuclease shRNA; sh-NC: Control shRNA.