Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway

Figure 2 Huangqin decoction improves adiposity and hepatic histological abnormalities in high-fat diet-induced nonalcoholic fatty liver disease rats. Data are presented as mean ± SD (n = 4–8). ^aP < 0.01 vs the normal group, ^bP < 0.05 and ^cP < 0.01 vs the high-fat diet group. A: Workflow of the experimental design; B: Dynamic curve of the body weight; C-E: Barcharts showing the effects of different treatments on body weight (C), liver weight at the termination of the experiment (D), and liver index (liver weight/body weight) (E) at the termination of the experiment; F and G: Representative micrographs of Hematoxylin and eosin and Oil Red O stained liver sections; H: Quantitative analysis of positive areas in Oil Red O staining. CMC-Na: Sodium carboxymethylcellulose; Fen: fenofibrate; HQD: Huangqin decoction; I.G.: Intragastric administration.