Fecal microbiota transplantation alleviates experimental colitis through the Toll-like receptor 4 signaling pathway

Figure 1 Fecal microbiota transplantation did not alleviate acute colitis induced by dextran sodium sulphate in Toll-like receptor 4 knockout mice. A: Body weight of mice during the course of colitis; B: The bar chart represents the disease activity index (DAI) score of mice on day 14; C: Representative images of colons from mice (left) and statistical analysis of colon length (right); D: Representative hematoxylin and eosin staining of colon tissues, original magnification 100 ×, and histological scores (right); E: Relative quantification of the transcription level of Toll-like receptor 4 (TLR4) among groups. ^aP < 0.05. DSS: Dextran sodium sulphate; FMT: Fecal microbiota transplantation; KO: Knockout.