Exploring the regulatory mechanism of tRNA-derived fragments 36 in acute pancreatitis based on small RNA sequencing and experiments

Figure 1 Identification of 116 upregulated tRNA-derived fragments and 95 downregulated tRNA-derived fragments in acute pancreatitis by the differential expression analysis. A: Heatmap of the differentially expressed tRNA-derived fragments (DE-tRFs); B: Volcano plot for the 116 upregulated and 95 downregulated DE-tRFs; C: Gene expression of the five most significant DE-tRFs using reverse transcription quantitative polymerase chain reaction. Error bars represent the mean ± SD, a and b represent different expression levels, the same letter represents no significant difference between groups (P > 0.05), different letters represent significant difference between groups (P < 0.05). AP: Acute pancreatitis; tRF: tRNA-derived fragment.