Incidence, prevalence, and comorbidities of chronic pancreatitis: A 7-year population-based study

Table 4 Available studies on comorbidities of chronic pancreatitis

Region	Study design	Study period	Total CP patients	Frequent comorbidities compared with controls	Ref.
Denmark	Nationwide retrospective cohort study	1995-2010	11972	Cerebrovascular disease, chronic pulmonary disease, ulcer disease, diabetes, chronic renal disease, and pancreatic cancer	[4]
United States and Denmark	Cross-sectional, multicenter prospective study	Not available	171	Anxiety and depression	[40]
United States	Retrospective cohort study	2015-2020	63230	Hypertension, diabetes, and myocardial Infarction	[41]
United States	Ongoing longitudinal cohort study	2017-2022	488	Depression, anxiety, sleep disturbance, and physical disability	[42]
United States	Cohort study (NAPS2 cohort)	2000-2014	1024	Gallstones, diabetes, heart disease/heart attack/stroke, liver disease, renal disease, or prior history of cancer	[25]
United Kingdom	Cohort Study (the United Kingdom BioBank cohort)	2000-2020	1027	Gallstones, hyperlipidemia, diabetes, hypertriglyceridemia, hypercalcemia, pancreatic cancer, celiac, and ulcerative colitis	[13]
Canada	Retrospective study	2007-2014	75744	Anxiety and depression	[43]
China	Population-based cohort study	2000-2011	15848	Urolithiasis	[44]
China	Population-based cohort study	2000-2011	17810	Subsequent pyogenic liver abscess	[45]
China	Population-based cohort study	2000-2011	16672	Cerebrovascular disease	[46]
China	Population-based cohort study	2000-2011	17778	Deep vein thrombosis and pulmonary embolism	[20]
China	Population-based cohort study	2000-2011	17796	Inflammatory bowel disease	[47]
China	Prospective observational study	2019-2021	720	Anxiety and depression	[48]