Incidence, prevalence, and comorbidities of chronic pancreatitis: A 7-year population-based study

Table 3 Prevalence of comorbidities in chronic pancreatitis patients

Diseases	Total cohort, n = 38090		Males, n = 23280		Females, n = 14810		P value
	n, %	Age, yr, mean ± SD	n, %	Age, yr, mean ± SD	n, %	Age, yr, mean ± SD
Total	100.00	57.58 ± 15.79	100.00	56.26 ± 15.25	100.00	59.99 ± 16.44	-
Diabetes	26.32	56.57 ± 14.60	28.94	55.43 ± 14.03	22.20	59.14 ± 15.51	< 0.001
Type I diabetes	0.79	45.33 ± 15.11	0.81	47.32 ± 12.81	0.76	42.23 ± 17.70	0.591
Type II diabetes	21.84	58.04 ± 14.26	23.73	56.78 ± 13.89	18.87	60.75 ± 14.66	< 0.001
Secondary diabetes	2.05	50.04 ± 13.24	2.71	49.35 ± 12.40	1.01	53.27 ± 16.27	< 0.001
Hypertension	21.51	66.32 ± 14.41	20.23	64.27 ± 14.43	23.51	69.36 ± 13.82	< 0.001
Cholelithiasis	16.79	62.33 ± 16.14	14.95	60.23 ± 15.37	19.67	64.90 ± 16.68	< 0.001
Dyslipidemia	16.70	51.49 ± 14.28	16.76	48.57 ± 13.12	16.61	56.01 ± 14.81	0.708
Cerebrovascular disease	12.76	69.75 ± 13.34	12.19	68.52 ± 13.55	13.65	71.60 ± 12.79	< 0.001
Ischemic cerebrovascular disease	11.75	69.55 ± 13.38	11.17	68.54 ± 13.57	12.65	71.09 ± 12.92	< 0.001
Hemorrhagic cerebrovascular disease	0.34	64.05 ± 14.42	0.43	62.63 ± 14.55	0.20	69.39 ± 12.79	< 0.001
Fatty liver disease	12.39	49.53 ± 13.50	13.46	47.20 ± 12.63	10.72	54.28 ± 13.96	< 0.001
Alcoholic fatty liver disease	0.35	54.07 ± 12.45	0.53	54.32 ± 12.38	0.07	50.50 ± 13.39	< 0.001
Coronary heart disease	10.07	72.15 ± 12.77	8.37	71.13 ± 13.10	12.75	73.27 ± 12.31	< 0.001
Heart failure	5.27	74.15 ± 13.38	4.72	72.62 ± 13.98	6.14	76.06 ± 12.33	< 0.001
Acute pancreatitis	5.08	51.38 ± 15.68	6.35	52.17 ± 14.18	3.07	48.80 ± 19.57	< 0.001
Hyperuricemia	4.93	56.86 ± 17.25	6.42	55.07 ± 16.87	2.59	64.28 ± 16.85	< 0.001
Ulcer disease	4.68	60.16 ± 14.54	5.28	59.30 ± 14.06	3.73	62.22 ± 15.46	< 0.001
Gastric ulcer	2.17	60.34 ± 13.91	2.40	59.36 ± 13.34	1.80	62.60 ± 14.92	< 0.001
Duodenal ulcer	1.30	59.15 ± 14.46	1.65	58.53 ± 14.65	0.74	61.28 ± 13.62	< 0.001
Liver cirrhosis/fibrosis	3.49	58.70 ± 13.92	4.35	57.05 ± 13.12	2.13	65.09 ± 15.04	< 0.001
Alcoholic cirrhosis	0.72	53.23 ± 10.21	1.15	53.31 ± 10.19	0.05	49.60 ± 10.54	< 0.001
Pancreatic pseudocyst	3.45	52.55 ± 14.28	4.46	51.57 ± 12.92	1.85	56.38 ± 18.17	< 0.001
Malnutrition	3.36	64.04 ± 16.53	3.80	62.74 ± 15.52	2.67	66.86 ± 18.23	< 0.001
Gastrointestinal bleeding	2.93	61.76 ± 16.38	3.46	59.78 ± 15.84	2.10	67.13 ± 16.64	< 0.001
Pancreatic tumor	2.65	61.43 ± 12.13	2.97	61.27 ± 11.77	2.15	61.79 ± 12.89	< 0.001
Malignant tumor of pancreas	2.36	61.74 ± 11.99	2.64	61.50 ± 11.67	1.91	62.27 ± 12.65	< 0.001
Osteoporosis	2.03	75.28 ± 13.19	1.37	70.13 ± 13.89	3.06	78.02 ± 11.94	< 0.001
Inflammatory bowel disease	0.14	56.13 ± 15.76	0.13	56.75 ± 14.03	0.17	55.43 ± 17.76	0.388
Crohn’s disease	0.03	56.40 ± 14.07	0.03	58.67 ± 10.76	0.03	53.00 ± 19.37	1
Ulcerative enteritis	0.12	56.00 ± 16.05	0.11	56.15 ± 14.56	0.14	55.83 ± 17.90	0.429