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World J Gastroenterol. Jan 21, 2023; 29(3): 521-535
Published online Jan 21, 2023. doi: 10.3748/wjg.v29.i3.521
Table 1 Main quantitative parameters extracted from perfusion computed tomography and magnetic resonance imaging imaging techniques to predict treatment response in patients with colorectal liver metastasis
Parameter name
Parameter definition
Parameter significance
Transfer constant (Ktrans)Rate of contrast extraction from the blood to the interstitiumIt reflects the balance between capillary permeability and BF in a tissue
Tissue interstitial volume (Ve)Volume of extravascular and extracellular contrast agent in a certain tissue, expressed as a percentageIt is a measure of cell density
Rate contrast (Kep)Rate at which the contrast agent returns from the extravascular-extracellular space to the vascular compartment (Kep = Ktrans/Ve)It reflects the tissue microcirculation and contrast agent permeability
Regional BFBF per unit volume or mass of tissue (mL of blood/min/100 mL of tissue)It expresses the rate of the delivery of nutrients and oxygen to a certain tissue