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©The Author(s) 2023.
World J Gastroenterol. Jul 28, 2023; 29(28): 4416-4432
Published online Jul 28, 2023. doi: 10.3748/wjg.v29.i28.4416
Published online Jul 28, 2023. doi: 10.3748/wjg.v29.i28.4416
Figure 5 Baclofen suppresses c-Myc and cyclin D1expression in cholangiocarcinoma cells.
A and B: The expression of c-Myc and cyclin D1, key proteins for cell proliferation, is suppressed in both cholangiocarcinoma cell lines after baclofen treatment. Western blots show the representatives of three biological replications with the same trends of results. Band intensities are the average of three biological replications which are normalized using the intensities of glyceraldehyde-3-phosphate dehydrogenase for each experiment. NG: Normal glucose; HG: High glucose; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.
- Citation: Saengboonmee C, Sorin S, Sangkhamanon S, Chomphoo S, Indramanee S, Seubwai W, Thithuan K, Chiu CF, Okada S, Gingras MC, Wongkham S. γ-aminobutyric acid B2 receptor: A potential therapeutic target for cholangiocarcinoma in patients with diabetes mellitus. World J Gastroenterol 2023; 29(28): 4416-4432
- URL: https://www.wjgnet.com/1007-9327/full/v29/i28/4416.htm
- DOI: https://dx.doi.org/10.3748/wjg.v29.i28.4416